Figures representing evidence of CPVT in three individuals with hRyR2 mutations. Top panels in each figure show example of bidirectional ventricular tachycardia reproducibly elicited by exercise stress testing. Lower left panels show single-strand conformation polymorphisms analyses with differences in banding among controls (CT) and affected individuals. Lower right panels show DNA sequence analyses demonstrating presence of mutations in the hRyR2 gene.
Courtesy Silvia G. Priori