|
Group
|
Incidence
|
Carrier Frequency
|
% Delta F508
|
%Common Caucasian Alleles
|
%Group-Specific Alleles
|
Sensitivity
|
|
Caucasians
|
1/3,300
|
1/29
|
70
|
13
|
-
|
80
|
|
Hispanics
|
1/8,9,000
|
1/46
|
46
|
11
|
-
|
57
|
|
Ashkenazi Jews
|
1/29
|
30
|
67
|
-
|
97
|
|
|
Native Americans
|
1/3970,
1/1,500 |
0
|
25
|
69
|
94
|
|
|
African Americans
|
1/15,300
|
1/60-65
|
48
|
4
|
23
|
75
|
|
Asian Americans
|
1/32,100
|
1/90
|
30
|
30
|
||
Source: Modified from Cutting GR. Genetic epidemiology and genotype/phenotype correlation. In: Program and abstracts. NIH Consensus Development Conference on Genetic Testing for Cystic Fibrosis. April 14-16, 1997. |
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