Phylogeny of the gene encoding N-acetylneuraminate lyase (Ensemb ID IGI_M1_ctg1425_20). Phylogenetic relationships for this gene among prokaryotes, protozoans and vertebrates were estimated using TREE-PUZZLE (13-15) from an amino acid alignment generated by CLUSTALX (13-15). Numbers at nodes are bootstrap support values obtained using neighbor joining of PAM-based distances estimated in PHYLIP (13-15) and puzzle support values (plain). Bacteria donated this gene to the protozoan parasite Trichomonas and to vertebrates such as humans and mice.

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