Number of Drosophila sequences related to human disease genes as a function of E-value. A graph of the percent of human disease genes with similar sequences in Drosophila as a function of E-value. Black-filled bars indicate the percent of human Locuslink entries (929 total) with matches to Drosophila sequences. White-filled bars indicate the percent of unique Drosophila sequences that match one or more human disease gene sequences. Note that even at E-values of 10-40, 54% of human disease genes have matches to Drosophila sequences.
Courtesy Genome Research