The gene structure and expression pattern of hABCA1. Panel A shows the location of 50 exons and 32 conserved noncoding sequences (CNSs) of hABCA1. These CNSs are regions of at least 75% sequence similarity between human and mouse extending over 120 bases or more. Two transcriptional start sites, one at exon 1 and the other at exon 1A, are found in humans. Panel B shows the relative expression levels of these transcripts in various tissues.
Courtesy Jan-Fang Cheng