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December 15, 2000
|
Picturing
the Fertile Genome:
New imaging technologies are predicting and improving the success
of in vitro fertilization |
Progress
on cancer gene chip with prognostic potential:
Microarray technology may help predict 'intermediate risk' outcomes
of diffuse large B-cell lymphoma |
First
complete plant genome yields bountiful harvest of genes:
Arabidopsis thaliana is sequenced by international collaboration |
Variation
in the RANTES gene increases risk of asthma and atopy |
Snipping
away at wild worms:
SNP collection in Hawaiian C. elegans strains |
Genetics, Epidemiology, and Ethics: A Proposal for Curriculum Reform
with an Introduction by Barbara J. Culliton |
|
December 8, 2000 |
A
Theory of Schizophrenia, Viruses and Pregnancy:
Millions of years ago, viruses hitched a ride on the primate genome.
What a long, strange trip it's been. |
Gene therapy successfully
treats arrhythmia in pig hearts |
Signs of aging
in the fruit fly:
Drosophila study identifies changes in gene expression linked
to age, stress |
New virus offers
gene therapy a boost |
Polymorphism discovered years
ago is linked to multiple sclerosis:
Mutation causes altered expression of the CD45 protein on surfaces
of immune cells |
|
December 1, 2000 |
Protein
Structure Becomes Crystal Clear:
The National Institute of General Medical Sciences launches 10-year
quest to determine the structures of 10,000 proteins |
Hemochromatosis
survey reveals disease-related conditions in relatives:
Findings 'emphasize the importance of screening relatives,' say
researchers |
Tracking
the cause of Huntington's disease:
In mice with a human mutation, gender of embryo contributes to instability |
Scientists
uncover a new gene therapy-targeting strategy for treating head
and neck cancers |
Estrogen
and heart disease in women:
Association between polymorphism in estrogen receptor gene and blood
pressure |
Medicine
through a Genetic Lens with an introduction by Barbara J. Culliton |
|
November 27, 2000 |
Fighting Tuberculosis
One Gene at a Time:
Scientists are searching the M. tuberculosis genome for ways
to disarm a virulent and persistent pathogen |
Beyond bad
parenting:
Attachment disorganization in infants is associated with a form
of the DRD4 gene |
Gene therapy
succeeds in mouse and rat models of diabetes |
Screening
for genes linked to p53 and cell suicide:
Researchers use microarrays to compare the activity of 5,730 genes
in tumor cells |
Paradox for RANTES
polymorphism:
SNP is associated with increased risk for HIV infection and delayed
progression to AIDS |
|
November 17, 2000 |
A
Test of Nerves:
Tracking the elusive touch receptor across three genomes yields
a gene required for sensing light touch |
Knocking out 19,000
worm genes, one by one:
Researchers report data on functional analyses of the C. elegans
genome |
Insect germ
warfare:
Scientists identify potential target used by Pyrrhocoris apterus
to eliminate bacteria |
Crystal structure
of a gene regulator identified |
An unlikely
suspect:
Variants of the thrombospondin gene increase risk of premature heart
attack |
Abraham
Lincoln's DNA, and Other Adventures in Genetics
By Philip R. Reilly |
|
November 10, 2000 |
The Stuff That
Finches are Made of:
A songbird's remarkable recovery from disease has scientists sequencing
part of the finch genome |
3-D structure
of virus protein suggests new approach for drug design |
Maspin gene as a marker
for breast cancer relapse |
Stem cells
track tumors |
Gene therapy
promotes survival of brain tissue and preserves memory |
Polymorphism
in interleukin-4 gene linked to severity of joint damage in rheumatoid
arthritis |
A Prescription
for Gene Therapy: The First Cabo Gene Therapy Working Group with
an introduction by Barbara J. Culliton |
|
November 3, 2000 |
Populations
and Polymorphisms:
Building the new science of environmental genomics |
Strong immune
response, polymorphisms in regulatory genes are linked to liver
disease in heavy drinkers |
Gene hunting
in the eye of the fly:
New Drosophila model of spinocerebellar ataxia type 1 |
Genes may
modify risk of lead poisoning |
New protein
senses salt balance in vertebrates |
SNPs reported
in the nicotine receptor CHRNB2 gene:
No association found between polymorphisms and smoking or nicotine
dependence |
Are We
Hardwired?: The Role of Genes in Human Behavior
By William R. Clark and Michael Grunstein |
|
October 27, 2000 |
Battling
Bacterial ResistanceShooting for the Genes |
Gene therapy
rejuvenates brain-damaged areas in monkeys with Parkinson's disease |
Precursors
of addiction:
Genetic and environmental influences on adolescent drug use |
Genome
scans and maximum number of drinks consumed in 24 hours indicate
alcoholism hotspot on chromosome 4 |
New gene
therapy approach in mouse model of Parkinson's disease |
Susceptibility
polymorphisms for drug abuse:
Heroin addiction and variants of the DRD4 gene in a Chinese population |
The Implications
of Genetics for Health Professional Education (part one) with
an introduction by Barbara J. Culliton |
|
October 20, 2000 |
In South
Africa, the Quagga Project Breeds Success:
Zebra breeding program creates offspring with traits of an extinct
relative |
Researchers
use gene therapy to starve tumors |
Neurospora
genome to be sequenced thanks to grant from National Science Foundation |
Researchers
on the trail of a molecular pathway that may lead to lung cancer
|
Hutterites
breathe new life into asthma research |
The genetics
of breathing free:
SNPs and the effectiveness of asthma medication |
Cats
Are Not Peas: A Calico History of Genetics
By Laura Gould |
|
October 13, 2000 |
Researchers
Spot A Region On Chromosome 10:
That May Be Associated with the Majority of Cases of Alzheimer's |
New hope
for cancer vaccines |
Cystic
fibrosis gene may be linked to sinus infections |
Two neurodegenerative
diseases linked to location on chromosome 9:
Researchers used genome scans to find region; gene is still at large |
Subtleties
of sight:
Polymorphism in APOE gene is linked to cognitive changes in middle
age |
Psychiatric
genetics: Back to the future with an introduction by Barbara J.
Culliton |
|
October 6, 2000 |
Give
and TakeEstonia's New Model for a National Gene Bank |
Some like it
salty:
Halobacterium genome sequenced |
Gene determines
tanning response and melanoma risk |
Risk
of breast and ovarian cancer in women with ancient mutations in
BRCA1 or BRCA2 |
Lethal genetic
muscle disorder corrected using enzyme therapy |
Anxiety
from infancy to adolescence:
Polymorphisms in the serotonin transporter gene and temperament
in children |
Introduction
by Barbara J. Culliton
A counterpoint
review of Matt Ridley's Genome by Kevin Davies, Ph.D |
|
September 29, 2000 |
Arrays Arrive
in the Brain:
Profiling the molecular response to seizure in the mouse brain |
Detecting
mutations:
Current gene tests not enough, according to recent study |
Thermoplasma
acidophilum:
Living the hot, acidic life |
Pinpointing
a susceptibility gene for type 2 diabetes |
Erasing the marks
of age:
Making old DNA young |
New method
of SNP discovery |
|
September 22, 2000 |
The DRD4 Gene:
Psychiatry's Repeat Offender:
After a chance discovery, another polymorphism in the dopamine D4
receptor gene is linked to attention deficit hyperactivity disorder |
Polymorphisms
increase risk for Down syndrome |
Deficiency
in taste buds leaves mice craving sweets |
Mitochondrial
genes play role in male infertility |
International
effort to investigate immune-related genes |
SNP chips
used to study cancer progression |
The
Second Creation: Dolly and the Age of Biological Control by
Ian Wilmut, Keith Campbell, and Colin Tudge |
|
September 15, 2000 |
The Evolving
Art of Arrays:
The molecular portraits of gene microarrays are creating new classifications
of disease. Here come the protein arrays. |
First
evidence recessive gene plays role in Alzheimer's disease |
Asthma susceptibility
gene found in mice |
Researchers reveal
cholesterol control mechanisms |
SNP in factor
VII gene may be protective:
Variation might explain absence of myocardial infarction in some
atherosclerosis patients |
|
September 8, 2000 |
Where
Quality Matters Most:
Chaperone genes, quality control and new views of disease |
Gene therapy
for hibernating hearts |
Buchnera:
the genomic evolution of a bacterium |
Nerve rescuers:
Cells from pig snouts reverse spinal cord damage in rats |
Mapping the
pig genome |
New protein
identified in Alzheimer's disease:
Nicastrin may be involved in processing disease-related proteins |
Book review
of Genes, Peoples, and Languages by Luigi Luca Cavalli-Sforza |
|
September 1, 2000 |
Recipes
for Perfection:
Genes, childhood and absolute pitch |
Closing
in on a new gene for breast cancer |
Hypocretin
deficiency may cause narcolepsy |
The
Pseudomonas aeruginosa genome:
Ubiquitous bacterium sequenced |
|
August 25, 2000 |
Why Dervishes
Whirl:
Sixty years later, scientists pinpoint the mutation behind a schoolboy's
spinning, deaf mouse |
Survivor
in the human genome:
Proposed human pheromone receptor is expressed in olfactory tissue |
Scientists link
gene to tumor metastasis |
Search for genetic
variation in early-onset alcoholism |
Sex and gender
in the literature:
Trendy use of 'gender' in biology blurs cultural distinctions, satisfies
few |
Jumping into
chromosome 2 |
Book review
of French DNA: Trouble in Purgatory by Paul Rabinow |
|
August 18, 2000 |
Mapping
the Most Primal Sense:
Odorant receptors and scent discrimination in Drosophila
|
This little piggy
goes to market, this little piggy is for transplants |
Estrogen
and heart disease in men:
Association between polymorphism and severity of disease |
Genetic analysis
of blood vessels and tumors hints at new targets for cancer therapy |
|
August 11, 2000 |
The Redwood
Genome:
Identifying redwood family trees sheds light on genetic variability |
Tracing
behavior to the brain:
A mutagenesis screen for psychiatric disease in mice |
DNA shuffle leads
to better virus |
Discovery
links BMPR2 gene to primary pulmonary hypertension |
Icelanders, a
diverse bunch? |
A book review
of The Cartoon Guide to Genetics by Larry Gonick and Mark
Wheelis |
|
August 4, 2000 |
Cholera
Genome Sequenced:
Sequence of cholera genome paves wave to new therapy |
Profiling
the placenta
Gene expression in mouse embryonic and placental tissues |
A leap
in gene function discovery |
Gene defect
in Margarita islanders may protect against herpes infection |
|
July 28, 2000 |
Seeds of
a New Medicine:
Genes, plants, and edible vaccines |
Defining
timeless:
Non-circadian role for mouse gene |
Fusing
genes for better vaccines |
Good genesBad
genes |
Genes, grapes
and the "French paradox" |
A
book review of Richard Lewontin's
It Ain't Necessarily So: The Dream of the Human Genome and Other
Illusions |
|
July 21, 2000 |
Genetic
Testing for Dogs |
Insulin-producing
cells grown in the lab offer hope to Type 1 diabetics |
Growing up
with divorce:
Evidence of genetic influence on child's adjustment |
Perplexing
X in non-Hodgkin's lymphoma |
Scientists
snare bear hair for DNA analysis |
|
July 14, 2000 |
The Skin
as Detoxifier |
Rethinking
imprinting:
Evidence of a common phenomenon in exotic pig cross |
Gene
therapy for beta-thalassemia successful in mice |
Gene
mutation linked to hypertension during pregnancy |
Genome
of bacteria Xylella fastidiosa, a threat to fruit and nut
crops, is sequenced |
Genetic
super heroes save world!
Exciting "X-Men" explode on screen |
|
June 30, 2000 |
Quirks of Genomic
Disease:
Palindromes, hairpins, and breakpoints |
Nano meets
Bio technology and sees SNPs |
The
Pingelapese colorblind:
New gene identified to shed light on rare vision disorder |
Cellular
alchemy |
The gene
responsible for social memory |
A review of
Matt Ridley's Genome |
|
June 23, 2000 |
The Pufferfish:
Clues to the human genome puzzle |
Shielding
the mother cells |
Mark of a drinker:
Alcohol and the genome |
Getting nervous |
Genetic
variant determines prognosis after heart attack |
|
June 16, 2000 |
For the Love
of Blood |
Meaningless
sex:
Hens eject sperm; roosters are clueless |
Combining
register data with genetic analyses for research on mental illness |
Provoking
panic:
Anxiety, psychology, and genetics |
Cataracts: Genes
vs. age and environment |
A review of Bernd Heinrich's
The Mind of the Raven |
|
June 9, 2000 |
An excerpt
from Robin Marantz Henig's
The Monk in the Garden: The Lost and Found Genius of Gregor Mendel,
the Father of Genetics
with an Introduction by Barbara J. Culliton |
Renaissance
cells:
Stem cells build tissue, fight tumors |
Mistakes
of the father:
Repair genes and infertility |
Are self-replicating
DNA elements helping plants adapt? |
Clickable
genomics:
Plans for virtual plant posted |
|
June 2, 2000 |
Riches of
the Brain Bank:
Seeking clues to mental illness, gene hunters discover proteins |
Genetic
inheritance may not be key to vast majority of childhood cancers |
Gene therapy
for brain tumors |
Genetic
surgery for muscular dystrophy in golden retrievers |
The Spanish flu
suspect:
Genes point to birds |
Sequencing
the Genome (primer) |
|
May 26, 2000 |
Silencing
of the Genes |
How many human
genes? |
The royal genome:
Swiss prize funds study of aging in ants |
Gene modifies
effect of estrogen on cognitive decline |
Bad
combination:
Neuroticism, a gene, and cigarettes |
|
May 19, 2000 |
Genes
and Antibiotic Resistance |
Mutation associated
with decreased breast cancer risk for women under 50 |
Genes hold the
key for transplant recipients |
High cholesterol
in young black males:
Genetic effect appears, then seems to disappear |
Damaging the
PKA gene drives mice to drink |
|
May 12, 2000 |
A Suicide
Gene:
Is there a genetic cause for suicide? |
Gene expression
in Huntington's disease |
Boundaries
between species |
Feedback loops:
How genomes mark time |
Butterflies
at the Academy:
New panel hears testimony on biotech foods; Varmus is co-chair |
Mechanism
of yeast telomerase enzyme revealed |
|
May 5, 2000 |
Unstable
Genomes and Cancer:
Eleven thousand mutations |
Round
two on genetic testing:
More public comment sought on oversight policy |
Genetic
testing for bipolar disorder:
A positive response to hypothetical questions |
Appetite gene suspected
in pigs |
|
April 28, 2000 |
Mapping
the Horse:
Targeting disease, scientists leave speed and endurance to breeders |
Impressive's
Flaw:
Muscle disease traces to popular sire |
All the
Pretty Horses:
Coat color genes at work |
New method
of gene therapy used to treat hemophilia B in mice |
Proteome
analysis may aid in diabetes research |
Island mice may
evolve faster:
From one species to six |
Obsessive compulsive
disorder: family members at higher risk |
|
April 21, 2000 |
Is There a Gene
for Shyness? |
Take the
Shyness Quiz |
Mood, food,
and anxiety:
The serotonin transporter gene |
Gene
links to heart health |
Cats and humans
share similar X and Y chromosomes |
Genetic code
for Listeria bacteria discovered |
Gene plus exercise
may reduce risk of coronary heart disease |
Europeans can
be traced to seven clans founded by seven women |
|
April 14, 2000 |
What
Makes Plants Grow?
The Arabidopsis genome knows |
SHATTERPROOF
genes in Arabidopsis are good news for agriculture |
DOE sequencing
chromosomes 5, 16 and 19 |
Gene
mutation affects the course of rheumatoid arthritis |
A tip for finding
elusive genes: use less bait |
Mutated ion
channel linked to progressive hearing loss |
Genomic catalog
of bladder tumors may aid diagnosis and therapy |
Abdominal
aneurysms: The first step in curing a disease: meet and talk |
|
April 7, 2000 |
Sex Differences
and Gene Expression in Autoimmune Disease |
Estrogen's
Protective Power Reaches the Brain |
Images
of Imprinting |
Sex matters:
Gender-based medical research |
People with
Down syndrome appear to have genes that protect against cancer |
Genes and
migraines |
National Research
Council urges greater regulation of genetically modified plants |
Birth control
for cockroaches |
Highlights
from the annual meeting of the American Association for Cancer Research |
|
March 31, 2000 |
Investigating
George C. Scott's Killer |
"Gene chip" studies
of aging genes |
A mutation
in the ATM gene may increase the risk of breast cancer |
Genes may influence
how much you smoke |
Building a
better silkworm with piggyBac |
Mutant
clock gene keeps fruit flies going |
Ancient DNA may
hold clue to HIV resistance |
Learning
our ABCs: The bacteria that cause meningitis |
|
March 24, 2000 |
The Humanized
Fly |
A fruitful
collaboration |
Assembling
the genome |
Exploring
Parkinson's disease, with a little help from flies |
Bacteria
use quick-switch genes to dodge host defenses |
New
genome sequence focuses search for type B meningitis vaccine |
Defect
in desmin gene responsible for distinct muscle disorder |
Researchers save oldest
tree in Europe |
Odors evoke musical
tunes |
A special crop - wine
with a barley gene |
|